The Effect of Exercise Training on Lean Body Mass in Breast Cancer Patients: A Systematic Review and Meta-analysis "Reduced lean body mass (LBM) is common during and after treatment for breast cancer, and it is associated with increased treatment-induced toxicity, shorter time to tumor progression, and decreased survival. Exercise training is a potential intervention [...]
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Myokine Expression and Tumor-Suppressive Effect of Serum after 12 weeks of Exercise in Prostate Cancer Patients on ADT Myokines a signalling molecules released from muscle both at rest, during and following exercise. Certain myokines have been demonstrated in laboratory experiments to suppress the growth of various cancer cells. This study has demonstrated for the first time [...]
This important study demonstrated that for patients with early stage breast cancer there was a direct relationship between lower physical fitness before commencing chemotherapy and significantly lower odds of achieving optimal relative dose intensity. In other words, lower fitness meant less chemotherapy tolerance, more side effects and greater reduction in dosage and so less effectiveness [...]
Resistance Training, Fatigue, Quality of Life, Anxiety in Breast Cancer Survivors This paper is noteworthy in that the researchers report a single resistance training session each week for 8 weeks produced meaningful improvements in physical functioning (+27%, p = 0.027); physical role functioning (+54%, p = 0.008); emotional role functioning (+42%, p = 0.027); [...]
Breast cancer and treatment impacts on muscle strength All patients with breast cancer or post treatment should perform at least two resistance training sessions per week to maintain muscle mass, strength and physical function. As expected these authors report that women who have undergone breast cancer treatment have lower muscle strength compared to matched [...]
Professor Newton was an invited speaker at the Cancer Prevention - Physical Activity Virtual Conference hosted by Cancer Research UK and Ludwig Cancer Research from 23-25 February 2021. Professor Newton presented on "Exercise as Medicine for Cancer" and covered a range of topics including: Exercise medicine across the cancer continuum Physical activity and exercise [...]
HIGH-INTENSITY INTERVAL VS. CONTINUOUS ENDURANCE TRAINING: PREVENTIVE EFFECTS ON HORMONAL CHANGES AND PHYSIOLOGICAL ADAPTATIONS IN PREDIABETES PATIENTS While this paper is not specifically in patients with cancer, pre-diabetes, diabetes and metabolic syndrome are very common health issues for cancer management and the systemic milieu that is produces definitely increases the growth rate and likelihood [...]
Does exercise intensity matter for fatigue during (neo-)adjuvant cancer treatment? The Phys-Can randomised clinical trial Researchers conducting this exercise medicine trial involving 577 patients report that high intensity combination exercise medicine produced significantly better cancer related fatigue outcome compared to low-moderate intensity although the difference was not clinically meaningful. Interestingly, the addition of behaviour [...]
Psychological distress in men with prostate cancer undertaking androgen deprivation therapy: modifying effects of exercise from a year-long randomized controlled trial Various supervised exercise modes (aerobic, resistance and impact loading) are effective in reducing psychological distress in men with prostate cancer on ADT. Those with the highest level of psychological distress improved the most. [...]
Compliance to aerobic and resistance training exercise prescription is higher for PT supervised versus group-based exercise The results of this study are somewhat expected but it was surprising that there was such a difference in resistance training intensity (73% 1RM versus 56% 1RM). Group-based exercise is more efficient, reducing cost for the patient and [...]