Does exercise intensity matter for fatigue during (neo-)adjuvant cancer treatment?
The Phys-Can randomised clinical trial
Researchers conducting this exercise medicine trial involving 577 patients report that high intensity combination exercise medicine produced significantly better cancer related fatigue outcome compared to low-moderate intensity although the difference was not clinically meaningful. Interestingly, the addition of behaviour change support had no effect for either group.
Unfortunately there was no usual care control which would have likely exhibited considerable declines in outcomes due to the cancer therapies.
There was no difference in exercise adherence between the groups or with or without behaviour change support.
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